Abstract: Objectives In order to meet the development trend of low weight and high strength of the pressure-resistant shell structure of deep-sea submersible， proposed a structural enhancement method which carbon fiber reinforced polymer(CFRP) winding circumferential inward corrugated compression shell， and the CFRP layer mode is optimized and analyzed. Methods Using ABAQUS， finite element simulation software， by changing the layer parameters of CFRP， according to the layer stress distribution of the composite layer， explored the optimal winding angle under the 14-layer CFRP layer and got the best laying method. And then， combined the relevant strength failure criteria， checked its intensity. Results The results indicate that： 40°is the best angle to wind CFRP to enhance circumferential inward corrugated compression shell，when the paving mode is (±40°2/±55°2/±70°2/90°2)， the stress distribution between the layers is relatively uniform. And as the strength of the structure fulfills the actual use requirements， it has a lighter weight. Conclusions The structure can reduce the overall weight of the deep-sea pressure-resistant shell， and push the development of the field toward lightweight design.